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tramadol is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). tramadol affects chemicals in the brain that may become unbalanced and cause anxiety.

tramadol is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

tramadol may also be used for purposes other than those listed in this medication guide.

tramadol XR should not be used if you are allergic to benzodiazepines, have a condition called acute narrow angle glaucoma, or are taking the anti-fungal medications ketoconazole or itraconazole. tramadol XR is not recommended for use in pregnancy. Therefore, let your doctor know if you are pregnant, if you are planning to become pregnant, or if you become pregnant while you are taking this medication. Let your doctor know if you are nursing

Paradoxical side effects are usually a result of too high a dose and/or combination with alcohol. Adjusting the dosage usually causes them to cease.

Concentrations of alprazolam in cigarette smokers may be reduced up to 50% when compared to non-smokers.

Long-term treatment with alprazolam may lead to physical and/or psychological dependence. Users often develop a tolerance to the drug's sedative effects, though tolerance to its anxiolytic efficacy rarely develops when used at therapeutic dosage levels.

tramadol is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). tramadol affects chemicals in the brain that may become unbalanced and cause anxiety.

tramadol is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

tramadol may also be used for purposes other than those listed in this medication guide.

tramadol XR should not be used if you are allergic to benzodiazepines, have a condition called acute narrow angle glaucoma, or are taking the anti-fungal medications ketoconazole or itraconazole. tramadol XR is not recommended for use in pregnancy. Therefore, let your doctor know if you are pregnant, if you are planning to become pregnant, or if you become pregnant while you are taking this medication. Let your doctor know if you are nursing

Paradoxical side effects are usually a result of too high a dose and/or combination with alcohol. Adjusting the dosage usually causes them to cease.

Concentrations of alprazolam in cigarette smokers may be reduced up to 50% when compared to non-smokers.

Long-term treatment with alprazolam may lead to physical and/or psychological dependence. Users often develop a tolerance to the drug's sedative effects, though tolerance to its anxiolytic efficacy rarely develops when used at therapeutic dosage levels.

tramadol is in a class of drugs called benzodiazepines. Approved by the FDA in 1981, controlled clinical trials have demonstrated that tramadol is effective in the treatment of Generalized Anxiety Disorder, anxiety associated with depression*, and Panic Disorder with or without agoraphobia. (Safety and effectiveness of tramadol in individuals below 18 years of age have not been established. For more Important Safety Information about tramadol, click here.)

How tramadol works is not known, but it is believed to affect some of the chemicals in the brain.

Recently, a new, once daily formulation of tramadol was approved by the FDA and is now available to patients. tramadol XR (tramadol-release tablets) is indicated for the treatment of Panic Disorder.